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GLP-2 (T) is a dual GIP and GLP-1 receptor agonist studied for its combined effects on insulin sensitivity and appetite.
By engaging both incretin pathways at once, the compound enhances glucose dependent insulin secretion while also reducing food intake through central appetite signaling.
In phase 3 trials, dual incretin agonists in this class produced average body weight reductions of 20 to 22%, findings that have made this mechanism a major focus of obesity research.